DVL1 (NP_877580, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. The sequence is MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTG
Conjugate
Unconjugated
Target
Alternative Names
DVL1; dishevelled segment polarity protein 1; DVL; DVL1L1; DVL1P1; segment polarity protein dishevelled homolog DVL-1; DSH homolog 1; dishevelled-1; dishevelled, dsh homolog 1; dishevelled 1 (homologous to Drosophila dsh);
DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
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