DNER (NP_620711, 368 a.a. ~ 476 a.a) partial recombinant protein with GST tag. The sequence is NEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSAC EEKVDLCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSP
DNER (delta/notch-like EGF repeat containing) is a protein-coding gene. Diseases associated with DNER include pathological gambling, and hepatitis b, and among its related super-pathways are Constitutive Signaling by NOTCH1 PEST Domain Mutants and NOTCH2 Activation and Transmission of Signal to the Nucleus. GO annotations related to this gene include clathrin binding and calcium ion binding. An important paralog of this gene is DLK2.
Pathway
Activated NOTCH1 Transmits Signal to the Nucleus; FBXW7 Mutants and NOTCH1 in Cancer; Signal Transduction; Signaling by NOTCH1
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