Specifications
Immunogen
A synthetic peptide of human DNAJB11 is used for rabbit immunization.
Target
Alternative Names
DNAJB11; DnaJ (Hsp40) homolog, subfamily B, member 11; dnaJ homolog subfamily B member 11; EDJ; ERdj3; HEDJ; DnaJ protein 9; human DnaJ protein 9; dnaJ protein homolog 9; APOBEC1-binding protein 2; PWP1-interacting protein 4; ER-associated DNAJ protein 3;
Product Background
Antigen Description
DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a C-terminal cysteine-rich region (Ohtsuka and Hata, 2000 [PubMed 11147971]).
Pathway
Activation of Chaperone Genes by XBP1(S), organism-specific biosystem; Activation of Chaperones by IRE1alpha, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem; Unfolded Protein Response, organism-specific biosystem.
Citations
Publication ()
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