Anti-DHX35 monoclonal antibody, clone FQS23494

Antibody Isotype

IgG

Clone

FQS23494

Species Reactivity

Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human DHX35 aa 650 to the C-terminus (C terminal) (Cysteine residue). The exact sequence is proprietary.Database link: Q9H5Z1

Conjugate

Application Notes

WB: 1/1000 - 1/5000;

Alternative Names

DHX35; DEAH (Asp-Glu-Ala-His) box polypeptide 35; C20orf15, DDX35, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 35; probable ATP-dependent RNA helicase DHX35; FLJ22759; KAIA0875; DEAH box protein 35; DEAH-box protein 35; DEAD/H (Asp-Glu-Ala-Asp/His) box

Entrez Gene ID

UniProt ID

Antigen Description

DEAD box proteins characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The function of DHX35 which is a member of this family, has not been determined.DEAD box proteins characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The function of this gene product which is a member of this family, has not been determined.

Pathway

Spliceosome, 35S U5-snRNP, organism-specific biosystem;