Anti-DDX41 (aa 523-622) polyclonal antibody

Species Reactivity

Human

Immunogen

DDX41 (NP_057306, 523 a.a. ~ 622 a.a) partial recombinant protein with GST tag. The sequence is TGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHCGDESMLDIGGERGC AFCGGLGHRITDCPKLEAMQTKQVSNIGRKDYLAHSSMDF

Conjugate

Alternative Names

DDX41; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; ABS; probable ATP-dependent RNA helicase DDX41; 2900024F02Rik; DEAD box protein 41; putative RNA helicase; DEAD-box protein abstrakt; DEAD box protein abstrakt homolog;

Entrez Gene ID

UniProt ID

Antigen Description

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene expression.

Pathway

Cytosolic sensors of pathogen-associated DNA; Immune System; Regulation of innate immune responses to cytosolic DNA;