Anti-DAZAP2 (aa 93-168) polyclonal antibody

Species Reactivity

Human

Immunogen

DAZAP2 (NP_055579, 93 a.a. ~ 168 a.a) partial recombinant protein with GST tag. The sequence is PVGPIYPPGSTVLVEGGYDAGARFGAGATAGNIPPPPPGCPPNAAQLAVMQGANVLVTQR KGNFFMGGSDGGYTIW

Conjugate

Alternative Names

DAZAP2; DAZ associated protein 2; PRTB; DAZ-associated protein 2; proline-rich transcript in brain; deleted in azoospermia associated protein 2; deleted in azoospermia-associated protein 2; proline-rich transcript, brain-expressed protein;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma. Multiple transcript variants encoding different isoforms have been found for this gene.

Pathway

Diurnally regulated genes with circadian orthologs;