Anti-Cytochrome P450 1A1 + 1A2 monoclonal antibody (DCABH-333)

Mouse anti-Rat Cytochrome P450 1A1 + 1A2 monoclonal antibody for WB, IHC-P, ICC/IF Datasheet

Bring this labeled antibody directly to your bench!

Online Inquiry Add to basket

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
ND2
Species Reactivity
Mouse, Human
Immunogen
3-methylcholanthrene induced Rat Cytochrome P450 1A1 + 1A2.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500; IHC-P: 1/50 - 1/200; ICC/IF: 1/20 - 1/200;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CYP1A1; cytochrome P450, family 1, subfamily a, polypeptide 1; cytochrome P450 1A1; CYPIA1; P450MT2; P450form6
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
Cytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in vertebrate physiology. The cytochrome P450 mixed-function monooxygenase system is probably the most important element of Phase I metabolism in mammals. P450s are membrane-bound, either in the inner membrane of mitochondria or in the endoplasmic reticulum of cells where they metabolise thousands of endogenous and exogenous compounds. In the liver, these substrates include toxins, drugs, and other unneeded and potentially harmful molecules. Humans have 18 families of cytochrome P450 genes and 43 subfamilies; the CYP1 family is involved in drug metabolism and includes 3 subfamilies, 3 genes and 1 pseudogene. The function about Cytochrome P450 1A1 + 1A2 antigen include aromatase activity; catalytic activity; demethylase activity; electron carrier activity; enzyme binding; enzyme binding; flavonoid 3-monooxygenase activity; heme binding; metal ion binding; monooxygenase activity; monooxygenase activity; oxidoreductase ac.
Pathway
Biological oxidations, organism-specific biosystem; Cytochrome P45 - arranged by substrate type, organism-specific biosystem; Fatty Acid Omega Oxidation, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of xenobiotics by cytochrome P45, organism-specific biosystem; Metabolism of xenobiotics by cytochrome P45, conserved biosystem.

Citations


Have you cited DCABH-333 in a publication? Let us know and earn a reward for your research.

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !

Online Inquiry

Name
Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: Anti-Cytochrome P450 1A1 + 1A2 monoclonal antibody

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket