Anti-SERPINB14 monoclonal antibody (CABT-36109MC)
Mouse anti-Chicken SERPINB14 monoclonal antibody for ELISA, WB
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Full length native protein (purified), isolated from chicken egg white formaldehyde treated and heat denatured by incubation for 1 h at 105oC.
ELISA: 1/8000; WB: 1/2000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
SERPINB14; ovalbumin; Allergen Gal d 2; CAP 2; CAP2; Cytoplasmic antiproteinase 2
This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. The function about SERPINB14 antigen include calcium ion binding; serine-type endopeptidase inhibitor activity.
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Kwon, CH; Park, HJ; et al. Serpin peptidase inhibitor clade A member 1 is a biomarker of poor prognosis in gastric cancer. BRITISH JOURNAL OF CANCER 111:1993-2002(2014).
Huang, ZQ; Li, HG; et al. SERPINB2 Down-Regulation Contributes to Chemoresistance in Head and Neck Cancer. MOLECULAR CARCINOGENESIS 53:777-786(2014).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.