Anti-Fibrillin 2 monoclonal antibody (DMAB9572)

Mouse anti-Chicken Fibrillin 2 monoclonal antibody for IP, WB, IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
JB3
Species Reactivity
Chicken
Immunogen
Fibrillin 2 from White Leghorn chicken embryos.
Conjugate
Unconjugated

Target


Alternative Names
CCA; congenital contractural arachnodactyly (Marfanoid-like); FBN2; FBN2_HUMAN; fibrillin 2 (congenital contractural arachnodactyly); Fibrillin-2

Product Background


Antigen Description
Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.

Citations


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References


DAHLBACK, K; SAKAI, LY; et al. ELASTOLYSIS IN LICHEN RUBER PLANUS. ACTA DERMATO-VENEREOLOGICA 71:364-366(1991).
Bussiere, CT; Wright, GM; et al. The mechanical function and structure of aortic microfibrils in the lobster Homarus americanus. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY 143:417-428(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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