Anti-Fibrillin 2 monoclonal antibody (DMAB9572)
Mouse anti-Chicken Fibrillin 2 monoclonal antibody for IP, WB, IHC
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Fibrillin 2 from White Leghorn chicken embryos.
CCA; congenital contractural arachnodactyly (Marfanoid-like); FBN2; FBN2_HUMAN; fibrillin 2 (congenital contractural arachnodactyly); Fibrillin-2
Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.
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Gourh, P; Arnett, FC; et al. Anti-fibrillin-1 antibody enhances the incorporation of fibrillin-1 into the extracellular matrix.. ARTHRITIS AND RHEUMATISM 54:S730-S730(2006).
Votteler, M; Berrio, DAC; et al. Elastogenesis at the onset of human cardiac valve development. DEVELOPMENT 140:2345-2353(2013).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.