Anti-Bursa Of Fabricius monoclonal antibody (DMAB9027)

Mouse anti-Chicken Bursa Of Fabricius monoclonal antibody for WB, IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
130-80-2
Species Reactivity
Chicken
Immunogen
chicken
Conjugate
Unconjugated

Target


Alternative Names
bursa of Fabricius; leukocyte, activated, cell surface glycoprotein

Product Background


Antigen Description
In birds, the bursa of Fabricius (Latin: Bursa cloacalis or Bursa fabricii) is the site of hematopoiesis, a specialized organ that, as first demonstrated by Bruce Glick and later by Max Cooper and Robert Good, is necessary for B cell (part of the immune system) development in birds. Mammals generally do not have an equivalent organ; the bone marrow is often both the site of hematopoiesis and B cell development. it is present in cloaca of birds It is named after Hieronymus Fabricius who described it in 1621.

Citations


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References


Humberd, J; Boyd, K; et al. Emergence of influenza A virus variants after prolonged shedding from pheasants. JOURNAL OF VIROLOGY 81:4044-4051(2007).
Jeurissen, SHM; Wagenaar, F; et al. Further characterization of M cells in gut-associated lymphoid tissues of the chicken. POULTRY SCIENCE 78:965-972(1999).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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