Anti-Bursa Of Fabricius monoclonal antibody (DMAB9027)
Mouse anti-Chicken Bursa Of Fabricius monoclonal antibody for WB, IHC
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bursa of Fabricius; leukocyte, activated, cell surface glycoprotein
In birds, the bursa of Fabricius (Latin: Bursa cloacalis or Bursa fabricii) is the site of hematopoiesis, a specialized organ that, as first demonstrated by Bruce Glick and later by Max Cooper and Robert Good, is necessary for B cell (part of the immune system) development in birds. Mammals generally do not have an equivalent organ; the bone marrow is often both the site of hematopoiesis and B cell development. it is present in cloaca of birds It is named after Hieronymus Fabricius who described it in 1621.
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Sayegh, CE; Rao, MA; et al. Avian B cell development: lessons from transgenic models. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 72:31-37(1999).
Sinha, RK; Alexander, C; et al. Regulated expression of peripheral node addressin-positive high endothelial venules controls seeding of B lymphocytes into developing neonatal rabbit appendix. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 110:97-108(2006).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.