Anti-Bursa Of Fabricius monoclonal antibody (DMAB9027)
Mouse anti-Chicken Bursa Of Fabricius monoclonal antibody for WB, IHC
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bursa of Fabricius; leukocyte, activated, cell surface glycoprotein
In birds, the bursa of Fabricius (Latin: Bursa cloacalis or Bursa fabricii) is the site of hematopoiesis, a specialized organ that, as first demonstrated by Bruce Glick and later by Max Cooper and Robert Good, is necessary for B cell (part of the immune system) development in birds. Mammals generally do not have an equivalent organ; the bone marrow is often both the site of hematopoiesis and B cell development. it is present in cloaca of birds It is named after Hieronymus Fabricius who described it in 1621.
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Tovari, J; Nemeth, I; et al. Cross-reacting lymphocyte antigens of domestic fowl and goose (Anser Anser Domesticus). CURRENT PROGRESS ON AVIAN IMMUNOLOGY RESEARCH, PROCEEDINGS :182-186(2001).
Feng, XL; Liu, QT; et al. Identification and Characterization of Novel Immunomodulatory Bursal-derived Pentapeptide-II (BPP-II). JOURNAL OF BIOLOGICAL CHEMISTRY 287:3798-3807(2012).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.