Anti-Optic Nerve monoclonal antibody (DMAB9543)
Mouse anti-Chicken Optic Nerve monoclonal antibody for IHC, IHC
Datasheet
Specifications
Host Species
Mouse
Antibody Isotype
IgM
Clone
8A2
Species Reactivity
Chicken
Immunogen
chick optic nerve
Conjugate
Unconjugated
Target
Alternative Names
optic nerve; cranial nerve 2
Product Background
Antigen Description
optic nerve, also known as cranial nerve 2, transmits visual information from the retina to the brain. Derived from the embryonic retinal ganglion cell, a diverticulum located in the diencephalon, the optic nerve does not regenerate after transection. The optic nerve is the second of twelve paired cranial nerves but is considered to be part of the central nervous system, as it is derived from an outpouching of the diencephalon during embryonic development.
Citations
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References
Birke, MT; Neumann, C; et al. Changes of Osteopontin in the Aqueous Humor of the DBA2/J Glaucoma Model Correlated with Optic Nerve and RGC Degenerations. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 51:5759-5767(2010).
Huang, W; Xing, W; et al. Localization and phenotype-specific expression of ryanodine calcium release channels in C57BL6 and DBA/2J mouse strains. EXPERIMENTAL EYE RESEARCH 93:700-709(2011).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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