Synthetic peptide corresponding to a region derived from internal residues of human cell division cycle 23
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:200-1:1000 IHC: 1:50-1:200
General Notes
This product (Catalog No. DPABH-17176) is a rabbit-derived IgG polyclonal antibody raised against human CDC23. This antibody exhibits cross-reactivity with CDC23 from mouse. It has been affinity purified by protein A. The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. DPABH-17176 is suitable for use in Western blot (WB) (1:200–1:1,000), IHC (1:50–1:200) applications. DPABH-17176 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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