Radial glial cells are a pivotal cell type in the developing central nervous system (CNS) involved in key developmental processes, from patterning and neuronal migration to their recently discovered role as precursors during neurogenesis. They arise early in development from neuroepithelial cells. Radial phenotype is typically transient, but some cells, such as Bergmann glia in the cerebellum and Muller glia in the retina, retain radial glia-like morphology postnatally. According to recent research, during the late stages of cortical development, radial glial cells divide asymmetrically in the ventricular zone to generate radial glial cells, postmitotic neurons and intermediate progenitor cells. Intermediate progenitor cells then divide symmetrically in the subventricular zone to generate neurons. During gliogenesis, radial glial cells differentiate into astrocytes.