Anti-CYP3A43 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human CYP3A43 is used for rabbit immunization.

Conjugate

Alternative Names

CYP3A43; cytochrome P450, family 3, subfamily A, polypeptide 43; cytochrome P450, subfamily IIIA, polypeptide 43; cytochrome P450 3A43; cytochrome P450 polypeptide 43; MGC119315; MGC119316;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms.

Pathway

Biological oxidations, organism-specific biosystem; Cytochrome P45 - arranged by substrate type, organism-specific biosystem; Drug metabolism - cytochrome P45, organism-specific biosystem; Drug metabolism - cytochrome P45, conserved biosystem; Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; Linoleic acid metabolism, organism-specific biosystem.