Anti-CYP1B1 polyclonal antibody (CPBT-66101RC)

Rabbit anti-Human CYP1B1 (aa 200-250) polyclonal antibody for IHC-P, WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Bovine, Chimpanzee, Dog, Horse, Monkey, Mouse, Rat, Zebrafish
Immunogen
Synthetic peptide sequence corresponding to a region between amino acids 200-250 of human CYP1B1 - conjugated to KLH.
Conjugate
Unconjugated

Applications


Application Notes
Immunohistology - Paraffin: Min Dilution 10ug/ml; Western Blotting: 0.5 - 1ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CYP1B1; cytochrome P450, family 1, subfamily B, polypeptide 1; CP1B; GLC3A; CYPIB1; P4501B1
Entrez Gene ID
UniProt ID
Q16678

Product Background


Pathway
AhR pathway; Arachidonic acid metabolism; Benzo(a)pyrene metabolism; Biological oxidations; Chemical carcinogenesis; Cytochrome P450 - arranged by substrate type; Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR); Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4);

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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Ulrike, B; Barbara, HH; et al. Characterisation of the xenobiotic-metabolizing Cytochrome P450 expression pattern in human lung tissue by immunochemical and activity determination. TOXICOLOGY LETTERS 164:278-288(2006).
Walker, NJ; Crofts, FG; et al. Induction and localization of cytochrome P4501B1 (CYP1B1) protein in the livers of TCDD-treated rats: detection using polyclonal antibodies raised to histidine-tagged fusion proteins produced and purified from bacteria. CARCINOGENESIS 19:395-402(1998).

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