Anti-CYP1B1 polyclonal antibody (CPBT-66101RC)
Rabbit anti-Human CYP1B1 (aa 200-250) polyclonal antibody for IHC-P, WB
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Human, Bovine, Chimpanzee, Dog, Horse, Monkey, Mouse, Rat, Zebrafish
Synthetic peptide sequence corresponding to a region between amino acids 200-250 of human CYP1B1 - conjugated to KLH.
Immunohistology - Paraffin: Min Dilution 10ug/ml; Western Blotting: 0.5 - 1ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
CYP1B1; cytochrome P450, family 1, subfamily B, polypeptide 1; CP1B; GLC3A; CYPIB1; P4501B1
AhR pathway; Arachidonic acid metabolism; Benzo(a)pyrene metabolism; Biological oxidations; Chemical carcinogenesis; Cytochrome P450 - arranged by substrate type; Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR); Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4);
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Carnell, DM; Smith, RE; et al. Target validation of cytochrome P450CYP1B1 in prostate carcinoma with protein expression in associated hyperplastic and premalignant tissue. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 58:500-509(2004).
Piipari, R; Savela, K; et al. Expression of CYP1A1, CYP1B1 and CYP3A, and polycyclic aromatic hydrocarbon-DNA adduct formation in bronchoalveolar macrophages of smokers and non-smokers. INTERNATIONAL JOURNAL OF CANCER 86:610-616(2000).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.