Synthetic peptide corresponding to a region derived from internal residues of human cullin 4B
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:200-1:1000
General Notes
This product (Catalog No. DPABH-05763) is a rabbit-derived IgG polyclonal antibody raised against human CUL4B. It has been affinity purified by protein A. This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. DPABH-05763 is suitable for use in Western blot (WB) (1:200–1:1,000) application. DPABH-05763 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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