Anti-CTSS monoclonal antibody (DCABH-6411)

Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
BU2G0
Species Reactivity
Human
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CTSS; cathepsin S; MGC3886; FLJ50259
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Endosomal/Vacuolar pathway, organism-specific biosystem;

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References


Reconstructing readiness: Young children's priorities for their early school adjustment

EARLY CHILDHOOD RESEARCH QUARTERLY

Authors: O'Farrelly, Christine; Booth, Ailbhe; Tatlow-Golden, Mimi; Barker, Beth

Young children in communities facing socioeconomic disadvantage are increasingly targeted by school readiness interventions. Interventions are stronger if they address stakeholders' priorities, yet children's priorities for early school adjustment are rarely accounted for in intervention design including selection of outcome measures. The Children's Thoughts about School Study (CTSS) examined young children's accounts of their early school experiences, and their descriptions of what a new school starter would need to know. Mixed-method interviews were conducted with 42 kindergarten children in a socioeconomically deprived suburb of Dublin, Ireland. First, inductive thematic analysis identified 25 priorities across four domains: feeling able and enthusiastic for school; navigating friendships and victimisation; supportive environments with opportunities to play; bridging school and family life. Second, deductive analysis compared children's priorities at item level against a school readiness outcome battery. Children's priorities were assigned to three groups: (1) assessed by outcome measures (core academic competencies, aspects of self-regulation); (2) partially assessed (self-efficacy, social skills for friendship formation and avoiding victimisation, creative thinking, play); and (3) not assessed by outcome measures (school liking, school environment, family-school involvement). This analysis derived from children's own perspectives suggests that readiness interventions aiming to support early school adjustment would benefit from considering factors children consider salient. It offers recommendations for advancing conceptual frameworks, improving assessment, and identifying new targets for supporting children and schools. In doing so we provide a platform for children's priorities to be integrated into the policies and practices that shape their early lives. (C) 2018 Elsevier Inc. All rights reserved.

Performance improvement of modified tubular solar still by employing vertical and inclined pin fins and external condenser: an experimental study

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Authors: Abdelgaied, Mohamed; Harby, Khalid; Eisa, Amr

The current experimental work aims to improve an accumulative yield of tubular solar distillers. This was achieved by utilizing the pin fins and external condenser coupled with the tubular solar distiller. The tubular distillers are characterized by having a large receiving and condensing surface area compared to a traditional single-slope distiller; therefore, the utilization of pin fins is very effective to increase the evaporation rate, as well as the external condenser was utilized to increase the condensation rate. In order to achieve this vision, the experimental study mainly included two axes: namely, in the first axis, the effect of utilizing the pin fins on the cumulative yield of tubular solar distillers was studied, as well as obtaining the optimal orientation of the pin fins to reduce the shadow effect generated inside the basin. In the second axis, the effect of utilizing an external condenser and the inclined pin fins on an accumulative yield of the tubular solar distiller was studied. To investigate this idea, in the first study axis, three tubular distillers were constructed and tested at the same conditions, namely conventional tubular solar still (CTSS), modified tubular solar still with vertical pin fins (MTSS-VPF), and modified tubular solar still with inclined pin fins (MTSS-IPF). In the second study axis, two tubular distillers were constructed and tested at the same conditions, namely CTSS and modified tubular solar still with inclined pin fins and condenser (MTSS-IPF+Condenser). The results presented that the enhancement in accumulative yield reached 18% and 27.6% for utilizing the vertical and inclined pin fins, respectively, as compared to CTSS. These results show that the utilization of inclined pin fins represents a good option to improve the accumulative yield of tubular distillers. Also, the accumulative yield and the daily efficiency achieved by utilization of the external condenser and the inclined pin fins (MHSS-IPF+Condenser) reached to 5.94 L/m(2)/day and 54.9% with an improvement of 70.2% and 71.6%, respectively, as compared to CTSS.

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