General Notes
This product (Catalog No. DPABH-09054) is a rabbit-derived polyclonal antibody raised against human CTSO, targeting the amino acid region 1–321 of the protein. This antibody exhibits cross-reactivity with Human CTSO from mouse and rat. It has been affinity purified by Protein A. Cathepsin O is a lysosomal papain-like cysteine proteinase of the CA clan, first described from human breast carcinoma tissue. Cathepsin O was found in all tissues analyzed, with greatest abundance in ovary, kidney, liver and placenta. Senescent fibroblasts are also reported to have elevated cathepsin O expression. Little is known about the localization of cathepsin O, but if it behaves similarly to the other CA cathepsins, the enzyme is divided between lysosomal and secreted forms.
DPABH-09054 is suitable for use in IP (0.5-4.0 μg for 1.0-3.0 mg of total protein lysate), IHC (1:50–1:500) applications.
DPABH-09054 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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