Anti-CST5 monoclonal antibody (DCABH-11151) Made to order

Rabbit anti-Human CST5 monoclonal antibody for WB, ELISA

View other CST5 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human CST5 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
CST5; cystatin D; cystatin-D; cystatin 5; cystatin-5; cysteine-proteinase inhibitor
Entrez Gene ID
UniProt ID

Product Background


Gene summary
CST5 (Cystatin D) is a Protein Coding gene. Among its related pathways are Endochondral Ossification and Salivary secretion. GO annotations related to this gene include cysteine-type endopeptidase inhibitor activity. An important paralog of this gene is CST2. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein found in saliva and tears. The encoded protein may play a protective role against proteinases present in the oral cavity.
Antigen Description
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein found in saliva and tears. The encoded protein may play a protective role against proteinases present in the oral cavity. Cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S > cathepsin H > cathepsin L > cathepsin B. Cystatin-D is a protein that in humans is encoded by the CST5 gene. 0The function about CST5 antigen include cysteine-type endopeptidase inhibitor activity; peptidase inhibitor activity; protein binding.
Pathway
Endochondral Ossification, organism-specific biosystem; Salivary secretion, organism-specific biosystem; Salivary secretion, conserved biosystem.

Citations


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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Kos, J; Obermajer, N; et al. Inactivation of harmful tumour-associated proteolysis by nanoparticulate system. INTERNATIONAL JOURNAL OF PHARMACEUTICS 381:106-112(2009).
Kabanda, A; Vandercam, B; et al. Low molecular weight proteinuria in human immunodeficiency virus-infected patients. AMERICAN JOURNAL OF KIDNEY DISEASES 27:803-808(1996).

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