Specifications
Species Reactivity
Mouse, Rat, Human, Rhesus monkey
Immunogen
E. coli-expressed, recombinant human G-CSF
Applications
Application Notes
ELISA: 5-10 μg/ml (as a capture antibody)
Target
Alternative Names
CD114; GCSFR
Product Background
Antigen Description
Granulocyte - colony stimulating factor (G-CSF) is a potent stimulator of bone marrow cells especially those of neutrophilic granulocyte lineage. In addition, G-CSF can enhance the survival and activate the immunological functions of mature neutrophils. G-CSF is produced primarily by monocytes and macrophages upon activation by endotoxin, TNF-alpha or IFN-gamma. The antibodyreacts with human granulocyte-colony stimulating factor (G-CSF).The antibody can neutralize the bioactivity of natural or recombinant G-CSF.
Citations
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Shimoji, K; Yuasa, S; et al. G-CSF Promotes the Proliferation of Developing Cardiomyocytes In Vivo and in Derivation from ESCs and iPSCs. CELL STEM CELL 6:227-237(2010).
Javierre, BM; Richardson, B; et al. A NEW EPIGENETIC CHALLENGE: Systemic Lupus Erythematosus. EPIGENETIC CONTRIBUTIONS IN AUTOIMMUNE DISEASE 711:117-136(2011).
COA
Certificate of Analysis
