Anti-CPA4 monoclonal antibody (DCABH-11109) Made to order

Rabbit anti-Human CPA4 monoclonal antibody for WB, ELISA

View other CPA4 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human CPA4 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
CPA4; carboxypeptidase A4; carboxypeptidase A3; CPA3
Entrez Gene ID
UniProt ID

Product Background


Gene summary
CPA4 (Carboxypeptidase A4) is a Protein Coding gene. Diseases associated with CPA4 include silver-russell syndrome and gliosarcoma. Among its related pathways are Transport to the Golgi and subsequent modification and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics. GO annotations related to this gene include metallocarboxypeptidase activity and carboxypeptidase activity. An important paralog of this gene is CPA3. This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness.
Antigen Description
This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. Metalloprotease that could be involved in the histone hyperacetylation pathway. Carboxypeptidase A4 is an enzyme that in humans is encoded by the CPA4 gene. 0The function about CPA4 antigen include metal ion binding; metallocarboxypeptidase activity; metallopeptidase activity; peptidase activity; zinc ion binding.

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References


Li, S; Sun, CX; et al. Chaperone-like effects of a scFv antibody on the folding of human muscle creatine kinase. PROTEIN ENGINEERING DESIGN & SELECTION 26:523-531(2013).

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