Anti-COQ7 monoclonal antibody (DCABH-11096) Made to order

Rabbit anti-Human COQ7 monoclonal antibody for WB, ELISA

View other COQ7 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human COQ7 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
COQ7; coenzyme Q7 homolog, ubiquinone (yeast); coenzyme Q, 7 (rat, yeast) homolog; ubiquinone biosynthesis protein COQ7 homolog; CAT5; CLK 1
Entrez Gene ID
UniProt ID

Product Background


Gene summary
COQ7 (Coenzyme Q7, Hydroxylase) is a Protein Coding gene. Diseases associated with COQ7 include coq7-related coenzyme q10 deficiency. Among its related pathways are Metabolism and Legionellosis. The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Alternatively spliced transcript variants have been found for this gene.
Antigen Description
The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Transcript variants have been described for this gene, but their full-length sequences have not been determined. Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner. The clk-1 (clock-1) gene encodes an enzyme (demethoxyubiquinone monooxygenase) that is necessary for ubiquinone biosynthesis in the worm Caenorhabditis elegans and other eukaryotes. The mouse version of the gene is called mclk-1 and the human, fruit fly and yeast homolog COQ7 (coenzyme Q biosynthesis protein 7). 0The function about COQ7 antigen include oxidoreductase activity; transition metal ion binding.
Pathway
Metabolic pathways, organism-specific biosystem; Ubiquinone and other terpenoid-quinone biosynthesis, organism-specific biosystem; Ubiquinone and other terpenoid-quinone biosynthesis, conserved biosystem; ubiquinol-1 biosynthesis (eukaryotic), conserved biosystem.

Citations


Have you cited DCABH-11096 in a publication? Let us know and earn a reward for your research.

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !
Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket

References


Jin, G; Kubo, H; et al. Saposin 1B is a human coenzyme Q10-binding/transfer protein. JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION 42:167-174(2008).

Online Inquiry

Name:
Phone: *
E-mail Address: *
Service & Products Interested: *
Project Description:
Verification Code: * Please input "diagnostics" as verification code.

Online Inquiry

  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket