Anti-COL4A3BP (aa 499-598) polyclonal antibody

Species Reactivity

Human

Immunogen

COL4A3BP (NP_112729, 499 a.a. ~ 598 a.a) partial recombinant protein with GST tag. The sequence is TWIVCNFSVDHDSAPLNNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVN PGGWAPASVLRAVAKREYPKFLKRFTSYVQEKTAGKPILF

Conjugate

Alternative Names

COL4A3BP; collagen, type IV, alpha 3 (Goodpasture antigen) binding protein; CERT; GPBP; CERTL; STARD11; collagen type IV alpha-3-binding protein; hCERT; ceramide transporter; ceramide transfer protein; lipid-transfer protein CERTL; StAR-related lipid tran

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene.

Pathway

Metabolism; Sphingolipid de novo biosynthesis;