Recombinant fusion protein of human Coilin (NP_004636.1).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:2000
General Notes
This product (Catalog No. DPABH-21787) is a rabbit-derived polyclonal antibody raised against human COIL. This antibody exhibits cross-reactivity with COIL from mouse and rat. It has been affinity purified by Protein A. The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. DPABH-21787 is suitable for use in Western blot (WB) (1:500–1:2,000) application. DPABH-21787 is supplied as a liquid formulation in PBS with 0.02% sodium azide,50% glycerol,pH7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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COA
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