Anti-CLOCK monoclonal antibody, clone FQS7338

Among all the arithmetic operations, division operation takes most of the clock cycles resulting in more path delay and higher power consumption. Many algorithms, including logarithmic division (LD), have been implemented to reduce the critical path delay and power consumption of division operation. However, there is a high possibility to further reduce these vital issues by using the novel approximate LD (ALD) algorithm. In the proposed ALD, a truncation adder is used for mantissa addition. Using this adder, the power delay product (PDP) and normalized mean error distance (NMED) are minimized. From the error analysis and hardware evaluation, it is observed that the proposed ALD using truncation adder (ALD-TA) with an appropriate number of inexact bits achieve lower power consumption and higher accuracy than existing LDs with exact units. The normalized mean error distance of 8-, 16-, and 32-bit ALD-TA is compared with LDs of same bits and observed a decrease of up to 21%, 20%, and 21%, and the PDP has a reduction of up to 33%, 51%, and 72%, respectively. Application of ALD-TA to image processing shows that high performance can be achieved by using ALDs than exact LDs.

Flowering time is an important agronomic trait that greatly influences plant architecture and grain yield in cereal crops. The present study identified a light-regulated gene, TaLWD1L-A, from hexaploid wheat that encodes a WD40 domain-containing protein. TaLWD1L-A was localized in the nucleus. Phenotypic analysis demonstrated that TaLWD1L-A overexpression in transgenic wheat led to an obvious early flowering phenotype. Upregulation of the floral activator gene TaFT1 caused the early flowering phenotype in transgenic wheat plants. TaLWD1L-A also affected the expression of circadian clock genes, including TaTOC1, TaLHY, TaPRR59, TaPRR73 and TaPRR95, and indirectly regulated the expression of the TaFT1 in transgenic plants by affecting the expression of vernalization-related genes TaVRN1 and TaVRN2 and photoperiod-related genes TaPpd-1 and TaGI. The early flowering phenotype in TaLWD1L-A-overexpressing transgenic lines led to a relatively shorter phenotype and yield reduction. Our results revealed that TaLWD1L-A affected the expression of circadian clock-related genes and played an important role in wheat flowering regulation by influencing the expression of genes related to vernalization and photoperiod pathways.