Anti-CLIC6 polyclonal antibody (DPABH-22292)
Rabbit anti-Human CLIC6 (aa 435-484) polyclonal antibody for WB
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Synthetic peptide corresponding to a region within the internal sequence amino acids 435-484 (RREDGEASEP RALGQEHDIT LFVKAGYDGE SIGNCPFSQR LFMILWLKGV) of Human CLIC6 (NP_444507).
WB: 0.5 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
CLIC6; chloride intracellular channel 6; CLIC1L; chloride intracellular channel protein 6; parchorin; chloride channel form A
CLIC6 (Chloride Intracellular Channel 6) is a Protein Coding gene. Among its related pathways are Hepatic ABC Transporters and Neuropathic Pain-Signaling in Dorsal Horn Neurons. GO annotations related to this gene include protein homodimerization activity and chloride channel activity. An important paralog of this gene is CLIC1. This gene encodes a member of the chloride intracellular channel family of proteins. The gene is part of a large triplicated region found on chromosomes 1, 6, and 21. Alternative splicing results in multiple transcript variants encoding different isoforms.
May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport (By similarity). Chloride intracellular channel protein 6 is a protein that in humans is encoded by the CLIC6 gene. 0The function about CLIC6 antigen include D2 dopamine receptor binding; D3 dopamine receptor binding; D4 dopamine receptor binding; protein C-terminus binding.
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Hechenberger, M; Schwappach, B; et al. A family of putative chloride channels from Arabidopsis and functional complementation of a yeast strain with a CLC gene disruption. JOURNAL OF BIOLOGICAL CHEMISTRY 271:33632-33638(1996).
Ignoul, S; Simaels, J; et al. Human ClC-6 Is a Late Endosomal Glycoprotein that Associates with Detergent-Resistant Lipid Domains. PLOS ONE 2:-(2007).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.