Specifications
Species Reactivity
Mouse; Rat; Guinea pig; Human
Immunogen
Synthetic peptide corresponding to N-terminal part of the second extracellular loop, amino acids 168-192 (VRTVEDGECYIQFFSNAAVTFGTAI) of Human Muscarinic Acetylcholine Receptor 2.
Applications
Application Notes
WB: 1/50; IHC-Fr: 1/50; ICC/IF: 1/50;
Target
Alternative Names
CHRM2; cholinergic receptor, muscarinic 2; muscarinic acetylcholine receptor M2; acetylcholine receptor; muscarinic 2; 7TM receptor; muscarinic M2 receptor; acetylcholine receptor, muscarinic 2; cholinergic receptor, muscarinic 2, isoform a; HM2; FLJ43243
Product Background
Antigen Description
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition.
Pathway
Amine ligand-binding receptors, organism-specific biosystem; Arf6 trafficking events, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Cholinergic synapse, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem;
Citations
Publication ()
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COA
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