Anti-CHPF (internal region) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthesized peptide derived from the internal region of human CHSS2.

Conjugate

Application Notes

WB: 1/500 - 1/1000; ELISA: 1/40000; IHC-P: 1/50 - 1/100; ICC/IF: 1/500 - 1/1000;

Alternative Names

CHPF; chondroitin polymerizing factor; CSS2; CHSY2; chondroitin sulfate synthase 2; chondroitin-polymerizing factor; N-acetylgalactosaminyltransferase 2; chondroitin glucuronyltransferase 2; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransfera

Entrez Gene ID

UniProt ID

Antigen Description

CHSS2 belongs to the chondroitin N-acetylgalactosaminyltransferase family. It has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity and transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. CHSS2 is ubiquitous; highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, small intestine and placenta.

Pathway

Chondroitin sulfate biosynthesis; Disease; Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate; Glycosaminoglycan biosynthesis, chondroitin sulfate backbone.