Anti-CETN1 polyclonal antibody (DPABH-22878)
Rabbit anti-Human CETN1 (aa 1-162) polyclonal antibody for WB
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Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1-162 of Human Centrin 1 (AAH29515).
WB: 1/500 - 1/3,000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
CETN1; centrin, EF-hand protein, 1; CEN1; CETN; centrin-1; caltractin
CETN1 (Centrin 1) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and microtubule binding. An important paralog of this gene is CETN2. The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle.
Plays a fundamental role in microtubule-organizing center structure and function. Centrin-1 is a protein that in humans is encoded by the CETN1 gene. It belongs to the centrin family of proteins. 0The function about CETN1 antigen include ATP binding; ATP-dependent helicase activity; G-protein beta/gamma-subunit complex binding; calcium ion binding.
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Laoukili, J; Perret, E; et al. Differential expression and cellular distribution of centrin isoforms during human ciliated cell differentiation in vitro. JOURNAL OF CELL SCIENCE 113:1355-1364(2000).
Middendorp, S; Paoletti, A; et al. Identification of a new mammalian centrin gene, more closely related to Saccharomyces cerevisiae CDC31 gene. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94:9141-9146(1997).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.