Full length protein corresponding to Human CENPC aa 1-542.Sequence: MAASGLDHLKNGYRRRFCRPSRARDINTEQGQNVLEILQDCFEEKSLAND FSTNSTKSVPNSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFV VEPSEATNRSVQAHEVHQKILATDVSSKNTPDSKKISSRNINDHHSEADE EFYLSVGSPSVLLDAKTSVSQNVIPSSAQKRETY
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/1000;
Target
Alternative Names
CENPC; centromere protein C; MIF2; hcp-4; CENP-C; CENPC1; CENP-C 1; centromere protein C 1; centromere autoantigen C; centromere autoantigen C1; interphase centromere complex protein 7;
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.
Pathway
Cell Cycle; M Phase; Mitotic Metaphase and Anaphase; Resolution of Sister Chromatid Cohesion
Citations
Publication ()
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