Full length protein corresponding to amino acids 1-402 of Human BRUNOL5, AAH47522.
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/1000;
Target
Alternative Names
CELF5; CUGBP, Elav-like family member 5; CELF-5; BRUNOL5; BRUNOL-5; CUGBP Elav-like family member 5; RNA-binding protein BRUNOL-5; CUG-BP and ETR-3 like factor 5; bruno-like 5 RNA binding protein;
RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
Citations
Publication ()
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COA
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