Synthetic peptide within Human CELF3 aa 2-32 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q5SZQ8
Conjugate
Unconjugated
Applications
Application Notes
Flow Cyt: 1/10 - 1/50; WB: 1/100 - 1/500;
Target
Alternative Names
CELF3; CUGBP, Elav-like family member 3; CAGH4; ERDA4; ETR-1; TNRC4; BRUNOL1; CUGBP Elav-like family member 3; CAG repeat domain; CAG repeat protein 4; bruno-like protein 1; RNA-binding protein BRUNOL-1; CUG-BP and ETR-3 like factor 3; CUG-BP- and ETR-3-l
RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
Citations
Publication ()
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