CDH23 (NP_071407, 29 a.a. ~ 114 a.a) partial recombinant protein with GST tag. The sequence is PFFTNHFFDTYLLISEDTPVGSSVTQLLAQDMDNDPLVFGVSGEEASRFFAVEPDTGVVW LRQPLDRETKSEFTVEFSVSDHQGVI
Conjugate
Unconjugated
Target
Alternative Names
CDH23; cadherin-related 23; USH1D; CDHR23; cadherin-23; otocadherin; cadherin-like 23; cadherin-related family member 23;
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.
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