Anti-CDCA7 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human CDCA7 is used for rabbit immunization.

Conjugate

Alternative Names

CDCA7; cell division cycle associated 7; JPO1; cell division cycle-associated protein 7; c-Myc target JPO1; cell division cycle associated protein 7;

Entrez Gene ID

UniProt ID

Antigen Description

This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

Pathway

Validated targets of C-MYC transcriptional activation;