Anti-CCRN4L (aa 64-152) polyclonal antibody

Species Reactivity

Human

Immunogen

CCRN4L (NP_036250, 64 a.a. ~ 152 a.a) partial recombinant protein with GST tag. The sequence is VCSMGTGTSRLYSALAKTLNSSAASQHPEYLVSPDPEHLEPIDPKELLEECRAVLHTRPP RFQRDFVDLRTDCPSTHPPIRVMQWNILA

Conjugate

Alternative Names

CCRN4L; CCR4 carbon catabolite repression 4-like (S. cerevisiae); NOC; CCR4L; Ccr4c; nocturnin; CCR4 protein homolog; circadian deadenylase NOC; carbon catabolite repression 4-like protein; CCR4-like (carbon catabolite repression 4, S.cerevisiae);

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector.

Pathway

BMAL1:CLOCK,NPAS2 activates circadian gene expression.