Specifications
Applications
Application Notes
ELISA: 0.1ug/ml
Target
Alternative Names
CAMP; cathelicidin antimicrobial peptide; CAP18; FALL 39; FALL39; LL37;29kDa cationic antimicrobial protein; CRAMP; HSD26; CAP-18; FALL-39;
Product Background
Antigen Description
Cyclic adenosine-3'5'monophosphate (cAMP) is the second messenger in the intracellular signal cascade, which is synthesis from adenosine triphosphate (ATP) by adenylyl cyclase. In the brain, cAMP signaling is involved in a multitude of mechanisms in neurons, astrocytes, oligodendrocytes and microglia. Examples are signal transduction in synapses, communication between neurons and glia cells or inflammatory processes. Alternations of cAMP affect normal brain functions; hence making cAMP a potential biomarkers for Parkinson'diseases, amyotrophic lateral sclerosis and Creutzfeldt-Jakob disease.
Pathway
Salivary secretion, organism-specific biosystem; Salivary secretion, conserved biosystem; Tuberculosis, organism-specific biosystem; Tuberculosis, conserved biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Zhang, GW; Lai, SJ; et al. Expression of cathelicidins mRNA in the goat mammary gland and effect of the intramammary infusion of lipopolysaccharide on milk cathelicidin-2 concentration. VETERINARY MICROBIOLOGY 170:125-134(2014).
Wan, M; van der Does, AM; et al. Antimicrobial peptide LL-37 promotes bacterial phagocytosis by human macrophages. JOURNAL OF LEUKOCYTE BIOLOGY 95:971-981(2014).
COA
Certificate of Analysis
