Anti-C1D (aa 1-141) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant fragment, corresponding to a region within amino acids 1-141 of Human C1D (UniProt Q13901).

Conjugate

Application Notes

WB: 1/500 - 1/3000.

Alternative Names

C1D; C1D nuclear receptor corepressor; C1D nuclear receptor co repressor; nuclear nucleic acid-binding protein C1D; LRP1; small unique nuclear receptor co repressor; SUN CoR; SUNCOR; C1D DNA-binding protein; nuclear DNA-binding protein; C1D nuclear recept

Entrez Gene ID

UniProt ID

Antigen Description

Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3-5 end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB.

Pathway

RNA degradation;