Anti-C-4-S And DS Neoepitope monoclonal antibody (DMAB8402)

Mouse anti-Bovine C-4-S And DS Neoepitope monoclonal antibody for ELISA, WB, IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG
Clone
3C7
Species Reactivity
Bovine
Immunogen
Bovine nasal cartilage aggrecan that had been deglycosylated with chondroitinase ABC digestion; i.e. BNC (ABC) Core.
Conjugate
Unconjugated

Target


Alternative Names
Chondroitin-4-sulfate; C-4-S; SODIUM CHONDROITIN SULFATE; chondroitin,4-(hydrogensulfate); chondroitin-4-sulfuricacid; chondroitinasulfate

Product Background


Antigen Description
Monoclonal antibody to delta-unsaturated glucuronic acid adjacent to N-acetylgalactosamine-4-sulphate in the non-reducing terminal dissacharide "stub" of 4-sulphated chondroitin sulphate that is produced after chondroitinase digestion of chondroitin-4-sulphate glycosaminoglycan chains (chondroitinase ABC or ACII) or dermatan sulphate glycosaminoglycan chains (chondroitinase ABC or chondroitinase B).

Citations


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References


Hultcrantz, M; BaggerSjoback, D; et al. Inner ear content of glycosaminoglycans as shown by monoclonal antibodies. ACTA OTO-LARYNGOLOGICA 116:25-32(1996).
Mizuno, S; Tateishi, T; et al. Hydrostatic fluid pressure enhances matrix synthesis and accumulation by bovine chondrocytes in three-dimensional culture. JOURNAL OF CELLULAR PHYSIOLOGY 193:319-327(2002).

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