Anti-Bacteria Monoclonal antibody (DMAB9440)

Mouse Anti-Bacteria Monoclonal antibody for WB, AP Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgM
Species Reactivity
Bacteria
Immunogen
Dental bacterial plaque from human
Conjugate
Unconjugated

Target


Alternative Names
Dental bacterial plaque

Product Background


Antigen Description
Dental plaque is a biofilm, usually a pale yellow, that develops naturally on the teeth. Like any biofilm, dental plaque is formed by colonizing bacteria trying to attach themselves to a smooth surface (of a tooth). It has been also speculated that plaque forms part of the defense systems of the host by helping to prevent colonization by microorganisms which may be pathogenic. The oral cavity contains the only known anatomical aspect of the human body that does not have a regulated system of shedding surfaces: the teeth. This allows a numerous amount of microorganisms to adhere to the surface of teeth for long periods of time. These multiple species of bacteria become dental biofilm. Dental biofilm, more commonly referred to as dental plaque, is composed of about a thousand bacteria that take part in the complex ecosystems of the mouth. The natural, non-frequent regulation of tooth shedding plays a large role in making dental biofilm the most diverse biofilm in the human body despite the relatively small size of the teeth.

Citations


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References


Russell, MW; Hajishengallis, G; et al. Secretory immunity in defense against cariogenic mutans streptococci. CARIES RESEARCH 33:4-15(1999).
Wardle, HM; et al. The challenge of growing oral spirochaetes. JOURNAL OF MEDICAL MICROBIOLOGY 46:104-116(1997).

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