Mouse Anti-Bacteria PKA-R Monoclonal antibody
In cell biology, Protein kinase A (PKA) refers to a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP-dependent protein kinase (EC 2. 7. 11. 11). Protein kinase A has several functions in the cell, including regulation of glycogen, sugar, and lipid metabolism. It should neither be confused with AMP-activated protein kinase-which, although being of similar nature, may have opposite effect -nor with cyclin-dependent kinases (Cdks).
Young, MRI; Lozano, Y; et al. Inhibition of tumor invasiveness by 1 alpha,25-dihydroxy-vitamin D-3 coupled to a decline in protein kinase A activity and an increase in cytoskeletal organization. CLINICAL & EXPERIMENTAL METASTASIS 15:102-110(1997).
Neary, CL; Nesterova, M; et al. Protein kinase A isozyme switching: eliciting differential cAMP signaling and tumor reversion. ONCOGENE 23:8847-8856(2004).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.