Mouse Anti-Bacteria PKA-R Monoclonal antibody
In cell biology, Protein kinase A (PKA) refers to a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP-dependent protein kinase (EC 2. 7. 11. 11). Protein kinase A has several functions in the cell, including regulation of glycogen, sugar, and lipid metabolism. It should neither be confused with AMP-activated protein kinase-which, although being of similar nature, may have opposite effect -nor with cyclin-dependent kinases (Cdks).
Neary, CL; Nesterova, M; et al. Protein kinase A isozyme switching: eliciting differential cAMP signaling and tumor reversion. ONCOGENE 23:8847-8856(2004).
Wu, J; Jones, JM; et al. Crystal structures of RI alpha subunit of cyclic adenosine 5'-monophosphate (cAMP)-dependent protein kinase complexed with (R-p)-adenosine 3',5'-cyclic monophosphothioate and (S-p)-adenosine 3',5'-cyclic monophosphothioate, the phosphothioate analogues of cAMP. BIOCHEMISTRY 43:6620-6629(2004).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.