Synthetic peptide within Human BVES aa 312-342 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q8NE79
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/10 - 1/50; WB: 1/100 - 1/500.
Target
Alternative Names
BVES; blood vessel epicardial substance; HBVES; POP1; POPDC1; popeye domain containing 1; popeye protein 1; popeye domain-containing protein 1; MGC42413;
Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading.
Citations
Publication ()
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COA
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