Anti-BUB3 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human BUB3 is used for rabbit immunization.

Conjugate

Alternative Names

BUB3; budding uninhibited; BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog; mitotic checkpoint protein BUB3; BUB3L; mitotic checkpoint component; budding uninhibited by benomyl; BUB3 budding uninhibited by benzimidazoles 3 homolog; hBUB3;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Pathway

APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem;