Anti-BPDE monoclonal antibody (DMAB27310)
Mouse anti-BPDE monoclonal antibody for ELISA, IP
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The antibody was raised against BPDE-I-G coupled to BSA.
Benzo[a]pyrene diol epoxide; Mouse Anti-BPDE Monoclonal Antibody ; Anti-BPDE Monoclonal Antibody ; BPDE Monoclonal Antibody Mouse Anti-BPDE MAb ; Anti-BPDE MAb ; BPDE MAb
The antibody recognizes both free polycyclic aromatic hydrocarbons (PAHs) and DNA adducts. In an inhibition assay, the binding of the antibody to BPDE adducts was inhibited by BPDE-I-DNA, BPDE-I-dG, BPDE-I tetraol but not by BPDE-II-DNA1.
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VANSCHOOTEN, FJ; HILLEBRAND, MJX; et al. IMMUNOCYTOCHEMICAL VISUALIZATION OF DNA ADDUCTS IN MOUSE-TISSUES AND HUMAN WHITE BLOOD-CELLS FOLLOWING TREATMENT WITH BENZO[A]PYRENE OR ITS DIOL EPOXIDE - A QUANTITATIVE APPROACH. CARCINOGENESIS 12:427-433(1991).
Zenzes, MT; Puy, LA; et al. Detection of benzo[a]pyrene diol epoxide-DNA adducts in embryos from smoking couples: evidence for transmission by spermatozoa. MOLECULAR HUMAN REPRODUCTION 5:125-131(1999).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.