Anti-BPDE monoclonal antibody (DMAB27310)

Mouse anti-BPDE monoclonal antibody for ELISA, IP Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
9F22
Species Reactivity
N/A
Immunogen
The antibody was raised against BPDE-I-G coupled to BSA.
Conjugate
Unconjugated

Target


Alternative Names
Benzo[a]pyrene diol epoxide; Mouse Anti-BPDE Monoclonal Antibody ; Anti-BPDE Monoclonal Antibody ; BPDE Monoclonal Antibody Mouse Anti-BPDE MAb ; Anti-BPDE MAb ; BPDE MAb

Product Background


Antigen Description
The antibody recognizes both free polycyclic aromatic hydrocarbons (PAHs) and DNA adducts. In an inhibition assay, the binding of the antibody to BPDE adducts was inhibited by BPDE-I-DNA, BPDE-I-dG, BPDE-I tetraol but not by BPDE-II-DNA1.

Citations


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References


VANSCHOOTEN, FJ; HILLEBRAND, MJX; et al. IMMUNOCYTOCHEMICAL VISUALIZATION OF DNA ADDUCTS IN MOUSE-TISSUES AND HUMAN WHITE BLOOD-CELLS FOLLOWING TREATMENT WITH BENZO[A]PYRENE OR ITS DIOL EPOXIDE - A QUANTITATIVE APPROACH. CARCINOGENESIS 12:427-433(1991).
Zenzes, MT; Puy, LA; et al. Detection of benzo[a]pyrene diol epoxide-DNA adducts in embryos from smoking couples: evidence for transmission by spermatozoa. MOLECULAR HUMAN REPRODUCTION 5:125-131(1999).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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