Recombinant fragment corresponding to BOLA3 aa 18-105.Sequence: GLPLHHRMFATQTEGELRVTQILKEKFPRATAIKVTDISGGCGAMYEIKI ESEEFKEKRTVQQHQMVNQALKEEIKEMHGLRIFTSVP Database link: Q53S33
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/200 - 1/500;
Target
Alternative Names
BOLA3; bolA family member 3; MMDS2; bolA-like protein 3; bolA homolog 3;
This gene encodes a protein that plays an essential role in the production of iron-sulfur (Fe-S) clusters for the normal maturation of lipoate-containing 2-oxoacid dehydrogenases, and for the assembly of the mitochondrial respiratory chain complexes. Mutation in this gene has been associated with multiple mitochondrial dysfunctions syndrome-2. Two alternatively spliced transcript variants encoding different isoforms with distinct subcellular localization have been reported for this gene (PMID:21944046).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Soreze, Y; Boutron, A; et al. Mutations in human lipoyltransferase gene LIPT1 cause a Leigh disease with secondary deficiency for pyruvate and alpha-ketoglutarate dehydrogenase. ORPHANET JOURNAL OF RARE DISEASES 8:-(2013).
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COA
Certificate of Analysis