Anti-BBS5 monoclonal antibody (DCABH-10718) Made to order

Rabbit anti-Human BBS5 monoclonal antibody for WB, ELISA

View other BBS5 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human BBS5 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
BBS5; Bardet-Biedl syndrome 5; Bardet-Biedl syndrome 5 protein; DKFZp762I194
Entrez Gene ID
UniProt ID

Product Background


Gene summary
BBS5 (Bardet-Biedl Syndrome 5) is a Protein Coding gene. Diseases associated with BBS5 include bardet-biedl syndrome 5 and bardet-biedl syndrome. Among its related pathways are Organelle biogenesis and maintenance and Cargo trafficking to the periciliary membrane. GO annotations related to this gene include RNA polymerase II repressing transcription factor binding and phosphatidylinositol-3-phosphate binding. An important paralog of this gene is ENSG00000251569. This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is required for the formation of cilia. Alternate transcriptional splice variants have been observed but have not been fully characterized.
Antigen Description
This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is required for the formation of cilia. Alternate transcriptional splice variants have been observed but have not been fully characterized. Bardet-Biedl syndrome 5 (BBS5) [MIM:615983]: A syndrome characterized by usually severe pigmentary retinopathy, early-onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. Secondary features include diabetes mellitus, hypertension and congenital heart disease. Bardet-Biedl syndrome inheritance is autosomal recessive, but three mutated alleles (two at one locus, and a third at a second locus) may be required for clinical manifestation of some forms of the disease. Note=The disease is caused by mutations affecting the gene represented in this entry. Bardet-Biedl syndrome 5 protein is a protein that in humans is encoded by the BBS5 gene. 0The function about BBS5 antigen include phosphatidylinositol-3-phosphate binding; protein binding.

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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Kagaya, A; Shimada, H; et al. Identification of a novel SEREX antigen family, ECSA, in esophageal squamous cell carcinoma. PROTEOME SCIENCE 9:-(2011).

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