Mouse Anti Aggregatibacter actiomycetemcomitans serotype a´ Hybridoma [373BB2.2] (CSC-H1787)

This hybridoma produces mAbs (IgM) against Aggregatibacter actiomycetemcomitans serotype a′

General Information


Immunogen
Aggregatibacter actiomycetemcomitans serotype a′
Isotype
IgM
Fusion Species
Mouse X Mouse Hybridoma
Immunological Donor
Female balb/c mouse spleen
Myeloma
Mouse F0
Clone
373BB2.2
Cell Line Description
The hybridoma produces monoclonal antibody against Aggregatibacter actiomycetemcomitans serotype a′
Application Notes
Cell binding; IF; WB; Antibody competition

Culture Method


Storage
Liquid nitrogen vapor phase.

Target


Introduction
Aggregatibacter actinomycetemcomitans (Aa) is an oral commensal found also in severe infections in the oral cavity, mainly the periodontium. A. actinomycetemcomitans, previously Actinobacillus actinomycetemcomitans, is a gram negative facultative non-motile rod. It is also associated with non-oral infections. Its role in periodontitis was first discovered by Danish-born periodontist J?rgen Slots, currently a professor of dentistry and microbiology at University of Southern California School of Dentistry. Bacterium actinomycetem comitans' was described by Klinger (1912) as coccobacillary bacteria isolated together with Actinomyces from actinomycotic lesions of man. It was reclassified as Actinobacillus actinomycetemcomitans by Topley & Wilson (1929) and as Haemophilus actinomycetemcomitans by Potts et al. (1985). The species has attracted attention because of its association with localized aggressive periodontitis.

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