Anti-AURKB polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Modified peptide

Conjugate

Application Notes

Immunofluorescence: 1/100 - 1/400; IHC: 1/50

Alternative Names

AURKB; aurora kinase B; serine/threonine kinase 12 , STK12; Aik2; AIM 1; ARK2; AurB; aurora 1; aurora B; IPL1; PPP1R48; protein phosphatase 1; regulatory subunit 48; STK5; ARK-2; STK-1; aurora-1; aurora-B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora-

Entrez Gene ID

UniProt ID

Antigen Description

Aurora B belongs to Serine/threonine kinase family, Aurora subfamily. Predicted molecular weight 39 kD. This kinase is highly expressed in thymus and many cancers and is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. Aurora B

Pathway

APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Aurora A signaling, organism-specific biosystem; Aurora B signaling, organism-specific biosystem; Aurora C signaling, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem;