Synthetic peptide conjugated to KLH, corresponding to a region within N-terminal amino acids 56-84 of Human ATP8B3 (NP_620168.1).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/100 - 1/500;
Target
Alternative Names
ATP8B3; ATPase, aminophospholipid transporter, class I, type 8B, member 3; ATPIK; probable phospholipid-transporting ATPase IK; ATPase, class I, type 8B, member 3; aminophospholipid translocase ATP8B3; potential phospholipid-transporting ATPase IK;
The protein encoded by this gene belongs to the synaptotagmin family. Synaptotagmins share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains, and are involved in calcium-dependent exocytosis of synaptic vesicles. This protein has been shown to be a key component of the secretory machinery involved in acrosomal exocytosis. Alternatively spliced transcript variants have been found for this gene.
Pathway
Ion channel transport; Transmembrane transport of small molecules.
Citations
Publication ()
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COA
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