Rabbit Anti-Human ATP6V1H (internal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human ATP6V1H.

Conjugate

Application Notes

IHC: 1:50-1:100

General Notes

This product (Catalog No. DPABH-19492) is a rabbit-derived IgG polyclonal antibody raised against human ATP6V1H. It has been affinity purified by protein A. This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
DPABH-19492 is suitable for use in IHC (1:50–1:100) application.
DPABH-19492 is supplied as a liquid formulation in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Vacuolar proton pump subunit H; EC 3.6.3.14; V-ATPase subunit H; V-ATPase 50/57 kDa subunits; Vacuolar proton pump subunit SFD

Entrez Gene ID

UniProt ID