Rabbit Anti-Human ATP2A1 (C-terminal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Synthetic peptide corresponding to residues near the C terminal of human ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

Conjugate

Application Notes

WB: 1:200-1:1000
IHC: 1:50-1:200

General Notes

This product (Catalog No. DPABH-21328) is a rabbit-derived polyclonal antibody raised against human ATP2A1. This antibody exhibits cross-reactivity with ATP2A1 from mouse. It has been affinity purified by Protein A. This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.
DPABH-21328 is suitable for use in Western blot (WB) (1:200–1:1,000), IHC (1:50–1:200) applications.
DPABH-21328 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

ATP2A; SERCA1

Entrez Gene ID

UniProt ID